A Quiz For The Future 

Sabarinath Mahadevan MD, DM, MRCP(Edin), SCE 
Assistant Professor, Madras Medical College, Chennai, India
  1. Which of the following CAR-T cell may be useful in management of lupus?

    1. CD19 CAR-T cell
    2. CD20 CAR-T cell
    3. BOTH
    4. Neither of above
  2. Which of the below cytokine would be potentially used to modulate Innate like lymphoid cells in AIRD?

    1. IL 33
    2. IL 10
    3. TGF beta
    4. TGF alpha
  3. Which of the following is not a part of HSCT therapy for AIRD?

    1. Use of G-CSF
    2. CD34+ infusion
    3. Use of ATG
    4. None of above
  4. Which of the following methods is used as a part of AI in AIRD to remove the weakest attribute?

    1. Recursive feature elimination
    2. Random forest model
    3. Linear regression model
    4. All of the above
  5. In preventive therapy for RA, which of the following would not be suitable target in pre clinical phase?

    1. Type 2 collagen
    2. Fibrinogen
    3. Biglycan
    4. All of the above
  6. Which among the following trial could be considered as example of precision medicine?

    1. R4RA
    2. SELECT
    3. FINCH
    4. AVERT
  7. Which of the following microbiota blooms is associated with SLE flares?

    1. R.gnavus
    2. P.copri
    3. Both
    4. None
  8. Which of the following could be a potential candidate for CRISPR-cas9 treatment in RA?

    1. MYC
    2. IFN GAMMA
    3. Mi125
    4. None of above
  9. Use of which of the following regenerative cells in AIRD may lead to ethical concerns?

    1. ESC
    2. iPSC
    3. MSC
    4. HSCT
  10. Patisiran-SiRNA drug is indicated in which of the following condition?

    1. Transthyretin mediated amyloidosis
    2. AA amyloidosis
    3. AM amyloidosis
    4. None

Answer Key:

1.a
2.a
3.d
4.a
5.a
6.a
7.a
8.a
9.a
10.a